Seroquel is used to treat schizophrenia.
This medicine is available in the following dosage forms: tablet, tablet, extended release.
Seroquel (Quetiapine) is used to treat schizophrenia, symptoms of bipolar disorder (manic-depressive illness).
Dosage and Administration
Seroquel should be taken orally with or without a food on regular schedule.
Depressive episodes associated with bipolar disorder:
The recommended initial adult oral dose is 50 mg once a day at bedtime. The dose usually is increased daily to reach 300 mg per day on the fourth day. Your doctor may increase your dose gradually if needed.
Manic episodes associated with bipolar disorder:
The recommended initial adult oral dose is 100 mg once a daily, taken in equal doses. Your doctor may increase your dose gradually if needed. However, the dose should not be more than 800 mg a day.
- Children - use and dose must be determined by your doctor.
If you miss a dose, take this medicine as soon as possible. Then go back to your regular dosing schedule. Do not double doses.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Keep out of the reach of children.
- Do not keep outdated medicine or medicine no longer needed.
Warning and Precautions
Do not use Seroquel if:
- You have an unusual or allergic reaction to this medicine or any other medicines
- Pregnancy category C
- You are taking a Bepridil, Cisapride, Mesoridazine, Terfenadine, Thioridazine
- You are a child; safety and effectiveness in children have not been confirmed.
- You have such diseases as
- Alzheimer's disease - Quetiapine may cause problems with swallowing, which may increase the chance of pneumonia; also, the chance of seizures may be increased.
- Blood vessel or circulation problems or
- Dehydration or
- Heart attack or stroke, history of or
- Heart disease or
- Heart failure or
- Heart rhythm problems or
- Hypotension (low blood pressure) or
- Hypovolemia (low blood volume) - may cause side effects to become worse.
- Breast cancer, or history of or
- Cataracts or
- Hyperlipidemia (increased blood cholesterol or fats) or
- Hyperprolactinemia (increased prolactin in the blood) or
- Seizures, history of or
- Underactive thyroid - use with caution. Quetiapine may make these conditions worse.
- Diabetes or
- Hyperglycemia - this medicine may raise your blood sugar levels.
- Kidney disease, severe or
- Liver disease - Higher blood levels of quetiapine may occur, increasing the chance of side effects; the dose may need to be changed.
Seroquel may raise your blood sugar. You may feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
Seroquel may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
Seroquel is contraindicated in patients with known hypersensivity to any component of the formulation.
Along with desirable effects, a medicine may cause some unwanted effects
- Cold sweats
- Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
- Sleepiness or unusual drowsiness
- Black, tarry stools
- Blurred vision
- Changes in patterns and rhythms of speech
- Chest pain
- Difficulty swallowing
- Fever, muscle aches, or sore throat
- Inability to move eyes
- Inability to sit still
- Increased blinking or spasms of eyelid
- Lip smacking or puckering
- Loss of balance control
- Mask-like face
- Need to keep moving
- Painful or difficult urination
- Puffing of cheeks
- Rapid or worm-like movements of tongue
- Shakiness in legs, arms, hands, or feet
- Shortness of breath
- Shuffling walk
- Slowed movements
- Slurred speech
- Sores, ulcers, or white spots on lips or in mouth
- Sticking out of tongue
- Stiffness of arms or legs
- Swelling of face, arms, hands, feet, or lower legs
- Swollen glands
- Trembling and shaking of hands and fingers
- Trouble in breathing, speaking, or swallowing
- Uncontrolled chewing movements
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Drug Abuse And Dependence
There were some cases of dependency occurs with SEROQUEL.