Low-Dose Estradiol Gel
BioSante Pharmaceuticals has received approval from the Food and Drug Administration (FDA) to market an estra-diol transdermal gel (Elestrin, formerly Bio-E-Gel) for menopausal women with moderate-to-severe hot flashes. Elestrin is a gel formulation of bio-identical estra-diol, the same estrogen produced naturally in women.
A metered dose applicator delivers 0.87 g of gel per actuation, allowing for precise titration for each dose. This is the lowest effective dose of estradiol available.
Elestrin is absorbed through the skin after it is applied on the upper arm. Estradiol generic is delivered to the bloodstream evenly over time in a non-irritating manner. The gel dries in one to two minutes.
The gel will be marketed in the U.S. by the Kenwood Therapeutics Division of Bradley Pharmaceuticals. It is scheduled to be launched this summer.
