Canadian Pharmacy Blog

Patients with bipolar disorder are less likely to attempt suicide if they are taking lithium carbonate (Eskalith®, Glaxo-SmithKline; Lithobid®, Solvay) rather than divalproex sodium (Depakote tablet, Abbott), the most commonly prescribed mood-stabilizing drug in the U.S. Researchers who analyzed data from 20,638 patients in two managed care organizations in California found that divalproex was associated [...]

GlaxoSmithKline and the FDA have warned doctors that the antidepressant paroxetine (Paxil) may raise the risk of suicidal behavior in young adults. The letter was accompanied by changes to the labeling of both Paxil and controlled-release Paxil Drug. A recent analysis of data on nearly 15,000 patients revealed a higher frequency of suicidal behavior in [...]