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FDA Alert: Linezolid (Zyvox) And Gram-Negative Infections

The FDA has alerted prescribers of new safety concerns about linezolid (Zyvox generic, Pfizer). A recent open-label, randomized trial compared linezolid with vancomycin (Vancocin, Viro Pharma), oxacillin (Bactocill, SmithKlineBeecham; Prostaphlin, Apothecon), or dicloxacillin (Dycill, GlaxoSmithKline; Dynapen, Apothecon) in seriously ill patients with intravascular catheter-related bloodstream and catheter-site infections. Patients receiving linezolid had a higher chance [...]

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