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Ezetimibe/Simvastatin Label Revision

The product label for generic ezetimibe/ medication simvastatin (Vytorin drug, Merck/Schering-Plough) may now show that it was more effective than generic rosuvastatin calcium (Crestor, AstraZeneca) in lowering low-density lipoprotein-cholesterol levels at all doses that were compared. In a study of 2,959 patients, high cholesterol levels were reduced by 52% to 61% with Vytorin 10/20 to [...]

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Ezetimibe plus Simvastatin: Better Together in Reducing Cardiac Risk Factors

Ezetimibe and simvastatin drug together were more effective in lowering low-density lipoprotein-cholesterol (LDL-C) and C-reactive protein (CRP) levels, compared with either drug as monotherapy, say researchers from University of Rochester, New York, and Methodist DeBakey Heart Center and Baylor College of Medicine in Houston, Texas. In three identical prospective trials, patients were randomly assigned to [...]

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