Serotonin-4 Receptor Agonist for IBS with Constipation
People with irritable bowel syndrome (IBS) have a lower gastrointestinal (GI) tract that might be more sensitive and work more slowly than it should, causing abdominal pain and discomfort, bloating, and altered bowel function (constipation and/or diarrhea). Drug Tegasrod maleate (Zelnorm generic, Novartis) activates serotonin-4 receptors, which stimulates peristaltic reflex and normalizes the impaired motility [...]





