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Less Nasogastric Tube Pain with Lidocaine

Both patients and clinicians agree that nasogastric tube insertion is very painful. But now that topical anesthesia is available, Australian researchers point out, why not use it? A double-blind, placebo-controlled trial from Royal Brisbane and Women’s Hospital, Royal Melbourne Hospital, and Austin Hospital, Australia, confirms that using topical anesthesia reduces the discomfort of nasogastric tube [...]

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DuPont’s $130 Million Facility

DuPont has opened a new facility in Old Hickory, Tennessee to produce a nonwoven composite fabric (Suprel™). Used for hospital operating gowns and patient drapes, the fabric combines the strength of polyester and the softness of polyethylene. It offers greater freedom of movement and comfort for patients. buy requip

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Tenofovir Gel: A New Microbicide for Women?

Tenofovir disoproxil fumarate (Viread, Gilead), an oral medication that inhibits retroviral replication, could have a new life as a convenient vaginal gel, say researchers from Harlem Hospital Center, Bronx-Lebanon Hospital/Center, University of Pennsylvania, and Miriam Hospital in Providence, Rhode Island. In the first phase 1 clinical trial to evaluate an antiretroviral agent as a vaginal [...]

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Skin Patch for ADHD

A methylphenidate transdermal system (Daytrana, Shire) offers another option for children six to 12 years of age with Attention Deficit Hyperactivity Disorder (ADHD). This is the first non-oral medication for ADHD. The patch, in strengths of 10, 15, 20 and 30 mg, is designed to be worn during a child’s normal daily activities. It should [...]

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Pramipexole for Restless Legs

Pramipexole dihydrochloride tablets (Mirapex, Boehringer Ingelheim) has been approved for the treatment of moderate-to-severe primary restless legs syndrome (RLS). RLS is a common neurological sensorimotor disorder. Patients typically describe an urge to move the legs, and they may experience burning, creeping, crawling, aching, tingling, or tugging sensations in the legs. Up to 10% of adults [...]

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Refrigerated Flu Vaccine For Next Season

Refrigerated FluMist live intranasal influenza virus vaccine (Medlmmune) has been approved. The vaccine is used to prevent influenza in healthy children and adolescents 5 to 17 years of age and in healthy adults 18 to 49 years of age. The new formulation, called CAIV-T (cold-adapted influenza vaccine-trivalent), can be stored in a refrigerator rather than [...]

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IV Route for Azacitidine In Myelodysplastic Syndromes

The FDA has approved a New Drug Application (NDA) supplement to add intravenous (IV) use as a new route of administration for azacitidine (Vidaza, Pharmion). This agent, which is indicated for the treatment of myelodys-plastic syndromes (MDS), may now be infused over a period of 10 to 40 minutes in a clinic or hospital setting. [...]

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