Ciclesonide Nasal Spray For Allergic Rhinitis
The FDA has approved ciclesonide nasal spray (Omnaris, Altana Pharma), a corticosteroid for treating nasal symptoms associated with seasonal and perennial allergic rhinitis (hay fever) in adults and in children 12 years of age and older.
The precise mechanism of action is unknown, although corticosteroids suppress the immune response.
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The safety and efficacy of the product were studied in four randomized, placebo-controlled clinical trials ranging in duration from two weeks to a year. Patients receiving the spray had an 8% to 10% greater reduction in nasal symptoms compared with subjects taking placebo.
Ciclesonide, under the trade name Alvesco, is also used in an inhaler in a liquid formulation for patients with asthma.
