Retapamulin (Altabax) Ointment for Impetigo
Retapamulin ointment (Altabax, Glaxo-SmithKline) has been approved for the topical treatment of impetigo caused by susceptible strains of Staphylococcus aureus or Streptococcus pyogenes, the two most common types of bacteria in this kind of infection.
Impetigo is considered a contagious infection of the skin’s top layers. It is most common among infants and children two to six years of age.
Altabax represents the first new class of prescription topical antibacterial agents (called pleuromutilins) to be approved by the FDA in nearly two decades. It is indicated for use twice daily for a five-day period in patients nine months of age and older; other prescription topical antibacterials may need to be used as much as three times daily for up to 12 days.
In vitro, this new topical antibiotic is considered to have a low potential for the development of resistance.
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To reduce the development of drug-resistant bacteria and to maintain the effectiveness of Altabax and other antibacterial drugs, this product should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.





